Products or potential products which are the subject of partnerships, joint ventures or licensing collaborations may be subject to differences between the partners. LEARN MORE The pharmaceutical giant is taking steps to remedy that deficiency by striking a deal: the acquisition of a UCB spinout thats already reached the clinic with a drug that takes a new approach to brain disorders and has potential applications that include Alzheimers disease. T+32.2.559.9588, isabelle.ghellynck@ucb.com. All rights reserved. About Syndesi Therapeutics Syndesi Therapeutics (www.syndesitherapeutics.com) has been established at the Centre d'Entreprises et d'Innovation (CEI) in Louvain-la-Neuve and will have a presence at the JLINX incubator facilities to access expertise at the Janssen campus in Beerse, Belgium. "I am delighted with the closing of this deal. Syndesi, which takes its name from the Greek word for connection, develops drugs that target synaptic vesicle protein 2A (SV2A), a protein that plays a key role in regulating neurotransmission. About Bone Therapeutics . When it comes to contacting clinicians and patients, the hospital switchboard can be just as [], AbbVie, alzheimer's disease, Clinical Trials, deals, life sciences M&A, neuroscience, North Chicago, UCB. Macrophage Therapeutics has developed a proprietary targeted steroid (MT-2000 class) designed to specifically treat the disease-causing cells quarterbacking the body's inflammatory response (Macrophages). SV2A plays a central role in synaptic transmission (connections between neurons). Pipeline Prospector delivers free access to a database of Neurology drugs under clinical trials which made headlines done by Syndesi Therapeutics X. AbbVie adds to neuroscience pipeline with $1bn Syndesi buy. The firm deploys the majority of its capital in Europe, with the balance in the United States. Dispersion and Wet Milling Technology for Pharmaceuticals, Supply Chain Support Services for Life Science Companies, Thank you for subscribing to Pharmaceutical Technology, The leading site for news and procurement in the pharmaceutical industry, Receive our newsletter - data, insights and analysis delivered to you. Fountain Healthcare Partners (www.fh-partners.com) is a life science focused venture capital fund with 176 million ($200 million) under management. This investment group formed Syndesi in 2017; the startup licensed SDI-118 from UCB in 2018. PIPELINE. Fountains main office is in Dublin, Ireland, with a second office in New York. A new whitepaper from Ventech Solutions offers helpful guidance for how to mitigate the hidden risks low-code platforms present. 3D Printing in Healthcare Market Size, Share, Trends Analysis Report By Region, Component (Hardware, Materials, Digital Marketing Trends in Colorectal Cancer. "Le dynamisme de notre activit, combin aux avances de notre pipeline, continue de soutenir les perspectives prometteuses d'AbbVie long terme." Sur une base GAAP, le ratio de marge brute du deuxime trimestre tait de 71,4 %. All rights reserved. The biotech notes that disruption of the synaptic connectivity is found in Alzheimers and other types of dementia. Synaptic dysfunction is believed to. 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Its current portfolio fair value is above 150 million . This acquisition gives AbbVie access to Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. Within the life science sector, specific areas of interest to Fountain include specialty pharma, medical devices, biotechnology and diagnostics. +972 77 555 8482 +31 35 808 0509 The lead molecule, SDI-118, is a small molecule currently in Phase 1b studies, which is being evaluated to target nerve terminals to enhance synaptic efficiency. COPENHAGEN, Denmark, March 1, 2022 /PRNewswire/ -- Novo Holdings, a leading international life sciences investor, today announces that its portfolio company Syndesi Therapeutics ('Syndesi'). document.getElementById('cloak45869').innerHTML += '' + addy45869+'<\/a>'; This page shows the latest Syndesi Therapeutics news and features for those working in and with pharma, biotech and healthcare. AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio. Get the latest industry news first when you subscribe to our newsletter. Our Pipeline Job Postings. Syndesi Therapeutics is funded by 9 investors. 2007 -2022 UCB S.A., Belgium. Innovative Med Concepts USA Private Innovative Med Concepts is a biotech company with a pipeline of novel treatments for fibromyalgia and other related . UCB has already developed and commercialized two products that address this target, the epilepsy drugs Keppra and Briviact. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. UCBs Neuroscience researchers in Belgium have designed a unique class of novel SV2A modulators. Connecting Health Systems and Life Science Researchers To Maximize the Potential of Real-world Evidence. Regulating synaptic transmission represents a promising approach to treating Alzheimer's Disease and other disorders with cognitive impairment. Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate synaptic function to relieve the symptoms of cognitive impairment. We are excited to see Syndesi develop our novel pro-cognitive SV2A modulators to create value for patients with cognitive impairment, said Dhavalkumar Patel, UCBs Chief Scientific Officer and Executive Vice President. 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The VIVES Louvain Technology Fund (www.vivesfund.com) is a multi-sector technology fund which invests in the spin-offs of the Universit catholique de Louvain (UCL) and start-ups in Belgium and neighboring countries. addy45869 = addy45869 + 'lamerie' + '.' + 'com'; By identifying and optimizing allosteric binding sites that have never before been targeted, Gain is unlocking new treatment options for difficult-to-treat disorders characterized by protein misfolding, including lysosomal storage disorders. North Chicago, Illinois-based AbbVie announced Tuesday that it paid $130 million up front to acquire Syndesi Therapeutics. UCB identified novel modulators of SV2A that show pro-cognitive properties in preclinical models. Founded in 1973, JJDC continues a legacy of customizing deals for data-driven companies across the continuum of healthcare, with the goal of turning great ideas into transformative new pharmaceutical, medical device and consumer healthcare products. With an upfront payment of $130 million, AbbVie gains Syndesi's portfolio of novel modulators of the synaptic vesicle protein 2A (SV2A), including its lead molecule SDI-118. //. MT . Syndesi was created through a partnership between UCB Biopharma SRL and a syndicate of Belgian and international investors to further develop novel SV2A modulators that had been originally discovered by UCB. V-Bio Ventures was established in 2015 and works closely with Belgium-based VIB, one of the worlds premier life science institutes. document.getElementById('cloak45869').innerHTML = ''; Under the deal, AbbVie also gained access to TeneoOne drug, TNB-383B, indicated to treat relapsed or refractory multiple myeloma. Therefore we make use of cookies. Milestone payments could bring shareholders of the biotech up to $870. Type MT-2000 is a class of agents that are designed to precisely convert pro-inflammatory M1 Macrophages to anti-inflammatory M2 macrophages. Disclosure of payments to Healthcare Professionals. IMPROVING THE LIVES OF PATIENTS AND THEIR FAMILIES. In June last year, AbbVie exercised an exclusive option for the acquisition of TeneoOne, a Teneobiosubsidiary. Syndesi Therapeutics is developing molecules which act in a unique way on the synaptic vesicle protein SV2A. The total value of the deal could. UCB - Inspired by patients. It has been a pleasure to partner with our investors to investigate the potential of SDI-118 in early clinical studies. The anchor of AbbVies neuroscience portfolio is probably botox. More from news Approximately 1 fully matching, plus 0 partially . 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About Syndesi Therapeutics Founded in December 2017 and based in Belgium, Syndesi is a clinical stage biotechnology company pioneering the development of novel therapeutics that modulate. - Expands AbbVie's neuroscience portfolio, adding first-in-class modulators of the synaptic vesicle protein 2A, including lead molecule SDI-118 currently in Phase 1b studies, - Novel mechanism will be evaluated for the potential to mitigate synaptic dysfunction associated with cognitive deficits across a range of neuropsychiatric and neurodegenerative disorders. UCB and investor syndicate led by Novo Seeds launch Syndesi Therapeutics to develop novel therapeutics for cognitive disorders, 2007 - 2022UCB S.A., Belgium. Back to companies UCB is listed on Euronext Brussels (symbol: UCB). See the full leadership team at Craft. www.jjdc.com. . Syndesi will build on a rich legacy of work by UCB to further develop these novel SV2A modulators to investigate their potential to improve cognition in diseases such as Alzheimers Disease, other dementias and cognitive impairment associated with schizophrenia. "There is a major unmet need for new therapies that can help improve cognitive function in patients suffering from difficult-to-treat neurologic diseases," saidTom Hudson, M.D., senior vice president, R&D, chief scientific officer, AbbVie. With more than 7500 people in approximately 40 countries, the company generated revenue of 4.2 billion in 2016. About UCB Ventures. Though the deal, AbbVie will gain access to Syndesis portfolio of SV2A modulators. read more 14 Dec AbbVie announced it has completed the acquisition of Syndesi Therapeutics SA, which will help to expand AbbVie's neuroscience portfolio. Follow @abbvie on Twitter, Facebook, Instagram, YouTubeand LinkedIn. The company is the holding company in the Novo Group, comprising Novo Nordisk A/S, Novozymes A/S and NNIT A/S, and is responsible for managing the Foundations assets. About Syndesi Therapeutics. The objective of the fund is to invest in the development of start-ups, from validation of the technology to commercial maturity. AbbVie has acquired Belgium-based company Syndesi Therapeutics in a deal worth up to $1bn, expanding its neuroscience portfolio.
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